Comparison of the Effectiveness of Fentanyl Adjuvant with Adrenaline Adjuvant on the Onset of Spinal Anesthesia in Lapatarai Regional Hospital, Barru Regency

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Hasmira Binti Hamsa

Abstract

Spinal anesthesia is a regional anesthesia technique widely used for lower body surgery. A rapid onset of anesthesia is crucial to support surgical effectiveness. The addition of adjuvants to local anesthetics may influence the onset and duration of anesthesia. Fentanyl and adrenaline are commonly used adjuvants, but their effectiveness in accelerating the onset of spinal anesthesia remains debated. This study employed a Quasi-Experimental design with a Post-test Only Non-equivalent Control Group. A total of 20 respondents were recruited and divided into two groups: the fentanyl group (n=10) and the adrenaline group (n=10). Samples were selected using purposive sampling. Data on the onset of spinal anesthesia were collected using observation sheets and analyzed with the Mann-Whitney test. Results: The mean onset of spinal anesthesia in the fentanyl group was 2.94 minutes, while in the adrenaline group it was 5.25 minutes. The Mann-Whitney test showed U = 5.500, Z = -3.349, p = 0.001, indicating a significant difference between the two groups. There is a significant difference between fentanyl and adrenaline as adjuvants in spinal anesthesia onset. Fentanyl is more effective in accelerating the onset of spinal anesthesia compared to adrenaline.

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How to Cite
Hamsa, H. B. (2026). Comparison of the Effectiveness of Fentanyl Adjuvant with Adrenaline Adjuvant on the Onset of Spinal Anesthesia in Lapatarai Regional Hospital, Barru Regency. Journal of Asian Multicultural Research for Medical and Health Science Study, 7(1), 11-18. https://doi.org/10.47616/jamrmhss.v7i1.708
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